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Side Effects & Safety for Sermorelin

Updated over 2 weeks ago

Sermorelin is generally well-tolerated and works by stimulating your body’s own growth hormone production rather than replacing hormones directly. While most people experience gradual and steady changes, some may notice mild side effects as their system adjusts. Your clinician will review your history to determine whether Sermorelin is appropriate for you.


Common, Mild Side Effects

Some individuals may experience mild or temporary effects, including:

  • Headache

  • Flushing or warmth, especially in the face

  • Temporary fatigue

  • Light dizziness

  • Increased appetite

  • Mild irritation at the administration site (if applicable to the formulation used)

These experiences are typically short-lived.

If symptoms persist or interfere with daily life, message your clinician.


Less Common Experiences

A smaller number of people may notice:

  • Vivid dreams or changes in sleep patterns

  • Mild water retention or bloating

  • Increased sensitivity to changes in exercise intensity or recovery

These responses often stabilize with consistent sleep, hydration, and training habits.


When to Contact Your Clinician

Message your clinician if you experience:

  • New or persistent headaches

  • Noticeable swelling or discomfort

  • Sleep disruption that doesn’t improve

  • Digestive changes that seem related

  • Any unexpected or unusual reaction

  • Changes in other medications or supplements

Your clinician can help determine whether your experience is within what’s expected or whether adjustments may be needed.


When to Seek Immediate Medical Care

Seek in-person medical attention if you experience:

  • Severe or worsening swelling

  • Trouble breathing

  • Chest pain

  • Signs of infection at an administration site (if applicable)

  • Rapid onset of severe symptoms

These events are rare but require urgent care.


Medication, Hormone, and Supplement Considerations

Tell your clinician if you:

  • Take medications that affect hormones

  • Use anabolic agents, stimulants, or performance supplements

  • Have a history of endocrine disorders

  • Recently started or stopped other hormone-related therapies

This helps ensure Sermorelin is appropriate and safely integrated into your routine.


Health Conditions to Discuss With Your Clinician

Be sure to inform your clinician if you have:

  • Sleep disorders

  • Thyroid conditions

  • Metabolic conditions

  • A history of pituitary issues

  • Recent surgeries or injuries

  • Cardiovascular concerns

These factors may influence whether Sermorelin is suitable for you.


Storage & Handling

Follow the instructions provided with your medication. Generally:

  • Store according to the guidance on the packaging

  • Keep out of direct heat or sunlight

  • Ensure it remains out of reach of children or pets

  • Inspect the product upon arrival

If anything appears damaged or off, please take photographs of the relevant items and Support can help.

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