This article applies specifically to the Weight Loss treatment plan.
Requirements may differ for other Maximus programs.
Side Effects & Safety for the Weight Loss Protocol
GLP-1 and GLP-1 + GIP medications used in the Weight Loss Protocol are well-studied and support weight loss and metabolic health.
Like all medications, they may cause side effects for some individuals. Your clinician determines whether this treatment is safe and appropriate based on your health history, symptoms, and lab results.
Common Side Effects
Many side effects are related to how these medications affect digestion and appetite. These may include:
mild nausea
diarrhea or loose stools
constipation
reduced appetite
occasional stomach discomfort
These effects are often temporary and may improve as your body adjusts.
If symptoms persist or become uncomfortable, you can message your clinician.
Less Common Effects
Some individuals may experience:
fatigue
bloating
mild headaches
changes in taste or food preferences
These experiences vary and are not necessarily a sign of a problem. Your clinician can help assess what is typical for you.
Serious or Concerning Symptoms
Although uncommon, certain symptoms may require prompt medical attention.
Seek urgent care if you experience:
severe abdominal pain
persistent vomiting
signs of dehydration
shortness of breath
chest pain
any severe or rapidly worsening symptom
For non-urgent concerns, message your clinician through your patient portal.
Managing Side Effects
If side effects occur, your clinician may provide guidance to help you manage symptoms.
Any adjustments to your treatment depend on:
your health history
your current treatment plan
how you are responding
Long-Term Safety Monitoring
Your clinician monitors your treatment over time to ensure it remains safe and appropriate.
This may include:
periodic lab testing
symptom check-ins
review of your overall health
evaluation of your response to treatment
All decisions are based on clinical judgment, your reported experience, and your lab results.
Medication Quality
Maximus works with pharmacy partners that source the base form of semaglutide and tirzepatide.
These medications match the active pharmaceutical ingredients used in clinical studies, helping ensure consistency and avoiding untested or chemically different variants.