No. Slightly high levels are caused just by stress and orgasming and are not an issue for most people.Related ArticlesHow does the Testosterone Protocol affect IGF levels?Are there benefits or drawbacks to cycling on and off the Testosterone Protocol?Does Testosterone Protocol cause low estrogen?What are the upper levels achieved by the Testosterone Protocol; anything above 800?If I currently have higher than normal estradiol levels would a SERM (such as Enclomiphene used in Testosterone Protocol) selectively block only new estradiol the medication might cause or would it block some of the current extra estradiol?